去甲熊去氧胆酸 (24-Nor-UDCA)

去甲熊去氧胆酸是侧链缩短的 UDCA 的 C23 同系物，较UDCA侧链少一个亚甲基，因对其对牛磺酸和甘氨酸亲和力相对较弱，使其易被胆管细胞重吸收回肝血窦与肝细胞，而促进胆管细胞的排泌作用。

24-去甲熊去氧胆酸具有有效的抗胆汁淤积，抗炎和抗纤维化的特性。属于特色原料药，用于治疗胆汁淤积性肝病，而且在原发性硬化性胆管炎治疗的临床试验中取得初步的效果。
  • 产品详情

产品名称: 去甲熊去氧胆酸

别名: Nor-Udca; 24-Norcholan-23-Oic Acid,3,7-Dihydroxy-,(3α,5β,7β)

分子式: C23H38O4

分子量: 378.55

CAS号: [99697-24-2]

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